77-year-old male
Treatment-naive
Published case · PMID 34524171
Lutetium-177 PSMA therapy as the first-line treatment for metastatic prostate carcinoma.
A 77-year-old gentleman presented with metastatic prostate carcinoma and significant pain — left leg weakness, left hip pain, and muscle wasting. With no prior treatment, the team initiated upfront Lu-177 PSMA-617 therapy. After two cycles, his PSA dropped from >2,000 ng/ml to 10.2 ng/ml with significant pain relief and improved quality of life.